Contact investigation for imported case of Middle East respiratory syndrome, Germany

Emerg Infect Dis. 2014 Apr;20(4):620-5. doi: 10.3201/eid2004.131375.

Abstract

On March 19, 2013, a patient from United Arab Emirates who had severe respiratory infection was transferred to a hospital in Germany, 11 days after symptom onset. Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) was suspected on March 21 and confirmed on March 23; the patient, who had contact with an ill camel shortly before symptom onset, died on March 26. A contact investigation was initiated to identify possible person-to-person transmission and assess infection control measures. Of 83 identified contacts, 81 were available for follow-up. Ten contacts experienced mild symptoms, but test results for respiratory and serum samples were negative for MERS-CoV. Serologic testing was done for 53 (75%) of 71 nonsymptomatic contacts; all results were negative. Among contacts, the use of FFP2/FFP3 face masks during aerosol exposure was more frequent after MERS-CoV infection was suspected than before. Infection control measures may have prevented nosocomial transmission of the virus.

Keywords: CoV; Germany; MERS; MERS-CoV; Middle East respiratory syndrome; United Arab Emirates; coronavirus; coronavirus infections; nCoV; respiratory infections; viruses.

MeSH terms

  • Adult
  • Aged
  • Animals
  • Camelus / virology
  • Coronavirus
  • Coronavirus Infections / transmission*
  • Cross Infection / transmission*
  • Cross Infection / virology
  • Female
  • Germany
  • Humans
  • Infection Control / methods
  • Male
  • Respiratory Tract Infections / transmission*
  • Respiratory Tract Infections / virology
  • Syndrome
  • United Arab Emirates