Nasal expiratory sound analysis for evaluation of nasal patency in perennial allergic rhinitis patients treated with nasal corticosteroids

ORL J Otorhinolaryngol Relat Spec. 2014;76(1):50-6. doi: 10.1159/000360996. Epub 2014 Apr 4.

Abstract

Purpose: To assess the efficacy of nasal expiratory sound analysis in determining the degree of nasal obstruction.

Materials and methods: We have analyzed and recorded the expiratory nasal sounds in 18 healthy controls and in 30 patients with inferior turbinate hypertrophy before and after the administration of nasal corticosteroid treatment. Analysis consisted of the time-expanded waveform, spectral analysis with time-averaged fast Fourier transform and waveform analysis of nasal sound.

Results: Before treatment, an increase in sound intensity at high frequency was observed in the sound analyses of the patients, whereas after treatment, a decrease in sound intensity at high frequency was noted in the sound analyses of the patients. The differences between the patients and the control group were statistically significant. Data obtained with the Odiosoft-Rhino method were correlated with symptom scores and endoscopic examination.

Conclusion: Expiratory nasal sound is a practical and objective tool, which can be reliably used not only for the assessment of the degree of nasal blockage but also for the comparison of different treatment alternatives.

MeSH terms

  • Administration, Intranasal
  • Adult
  • Animals
  • Anti-Allergic Agents / therapeutic use*
  • Case-Control Studies
  • Female
  • Humans
  • Immunoglobulin E / blood
  • Male
  • Mometasone Furoate
  • Nasal Obstruction / drug therapy*
  • Pregnadienediols / therapeutic use*
  • Pyroglyphidae / immunology
  • Reproducibility of Results
  • Rhinitis, Allergic, Perennial / drug therapy*
  • Rhinitis, Allergic, Perennial / immunology
  • Rhinometry, Acoustic*
  • Signal Processing, Computer-Assisted
  • Skin Tests

Substances

  • Anti-Allergic Agents
  • Pregnadienediols
  • Mometasone Furoate
  • Immunoglobulin E