P-glycoprotein makes no contribution to the lower transplacental transfer of digoxin under fetal heart failure, but who should be blamed for?

Eur J Obstet Gynecol Reprod Biol. 2014 Aug:179:256-7. doi: 10.1016/j.ejogrb.2014.04.020. Epub 2014 Apr 26.

Authors

Yifei Li¹, Yimin Hua¹, Kaiyu Zhou²

Affiliations

¹ West China Second Hospital, Pediatric Cardiology, No.20 3rd Section of Southern Renmin Road, Chengdu 610041, China.
² West China Second Hospital, Pediatric Cardiology, No.20 3rd Section of Southern Renmin Road, Chengdu 610041, China. Electronic address: kaiyuzhou313@163.com.

PMID: 24798074
DOI: 10.1016/j.ejogrb.2014.04.020

No abstract available

Publication types

Letter

MeSH terms

ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism*
Animals
Cardiotonic Agents / pharmacokinetics*
Cardiotonic Agents / therapeutic use
Digoxin / pharmacokinetics*
Digoxin / therapeutic use
Female
Fetal Diseases / drug therapy
Fetal Diseases / metabolism*
Heart Failure / drug therapy
Heart Failure / metabolism*
Maternal-Fetal Exchange*
Pregnancy
Rats
Rats, Sprague-Dawley

Substances

ATP Binding Cassette Transporter, Subfamily B, Member 1
Cardiotonic Agents
Digoxin