ED disposition of the Glasgow Coma Scale 13 to 15 traumatic brain injury patient: analysis of the Transforming Research and Clinical Knowledge in TBI study

Am J Emerg Med. 2014 Aug;32(8):844-50. doi: 10.1016/j.ajem.2014.04.003. Epub 2014 Apr 13.

Abstract

Objective: Mild traumatic brain injury (mTBI) patients are frequently admitted to high levels of care despite limited evidence suggesting benefit. Such decisions may contribute to the significant cost of caring for mTBI patients. Understanding the factors that drive disposition decision making and how disposition is associated with outcomes is necessary for developing an evidence-base supporting disposition decisions. We evaluated factors associated with emergency department triage of mTBI patients to 1 of 3 levels of care: home, inpatient floor, or intensive care unit (ICU).

Methods: This multicenter, prospective, cohort study included patients with isolated head trauma, a cranial computed tomography as part of routine care, and a Glasgow Coma Scale (GCS) score of 13 to 15. Data analysis was performed using multinomial logistic regression.

Results: Of the 304 patients included, 167 (55%) were discharged home, 76 (25%) were admitted to the inpatient floor, and 61 (20%) were admitted to the ICU. In the multivariable model, admission to the ICU, compared with floor admission, varied by study site, odds ratio (OR) 0.18 (95% confidence interval [CI], 0.06-0.57); antiplatelet/anticoagulation therapy, OR 7.46 (95% CI, 1.79-31.13); skull fracture, OR 7.60 (95% CI, 2.44-23.73); and lower GCS, OR 2.36 (95% CI, 1.05-5.30). No difference in outcome was observed between the 3 levels of care.

Conclusion: Clinical characteristics and local practice patterns contribute to mTBI disposition decisions. Level of care was not associated with outcomes. Intracranial hemorrhage, GCS 13 to 14, skull fracture, and current antiplatelet/anticoagulant therapy influenced disposition decisions.

Trial registration: ClinicalTrials.gov NCT01565551.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Anticoagulants / therapeutic use
  • Brain Injuries / diagnosis
  • Brain Injuries / diagnostic imaging
  • Brain Injuries / drug therapy
  • Brain Injuries / therapy*
  • Emergency Service, Hospital / statistics & numerical data*
  • Female
  • Glasgow Coma Scale / statistics & numerical data*
  • Hospitalization / statistics & numerical data
  • Humans
  • Intensive Care Units / statistics & numerical data
  • Intracranial Hemorrhage, Traumatic / diagnosis
  • Intracranial Hemorrhage, Traumatic / diagnostic imaging
  • Intracranial Hemorrhage, Traumatic / therapy
  • Logistic Models
  • Male
  • Neuroimaging
  • Neuropsychological Tests
  • Patient Outcome Assessment
  • Platelet Aggregation Inhibitors / therapeutic use
  • Prospective Studies
  • Tomography, X-Ray Computed
  • Triage / statistics & numerical data

Substances

  • Anticoagulants
  • Platelet Aggregation Inhibitors

Associated data

  • ClinicalTrials.gov/NCT01565551