Increased risk for lymphoma following hemorrhagic fever with renal syndrome

Jonas Klingström; Fredrik Granath; Anders Ekbom; Niklas K Björkström; Hans-Gustaf Ljunggren

doi:10.1093/cid/ciu488

Increased risk for lymphoma following hemorrhagic fever with renal syndrome

Clin Infect Dis. 2014 Oct 15;59(8):1130-2. doi: 10.1093/cid/ciu488. Epub 2014 Jun 25.

Authors

Jonas Klingström¹, Fredrik Granath², Anders Ekbom², Niklas K Björkström³, Hans-Gustaf Ljunggren¹

Affiliations

¹ Center for Infectious Medicine, and.
² Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.
³ Center for Infectious Medicine, and Liver Immunology Laboratory, Division of Gastroenterology and Hepatology, Department of Medicine, Karolinska University Hospital Huddinge, Karolinska Institutet.

PMID: 24965350
DOI: 10.1093/cid/ciu488

Abstract

Hemorrhagic fever with renal syndrome (HFRS) is a severe acute disease. Although long-term consequences to public health have been reported, no association with cancer is known. We examined the risk of cancer development after HFRS in the Swedish population between 1997 and 2011 (n = 6582) and report a 73% increased risk for lymphoma.

Keywords: HFRS; Puumala virus; hantavirus; lymphoma.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Female
Hemorrhagic Fever with Renal Syndrome / complications*
Humans
Lymphoma / epidemiology*
Male
Middle Aged
Risk Assessment
Sweden / epidemiology
Young Adult