Abstract
The prevalence of atherosclerosis (ATH) is higher in patients with systemic lupus erythematosus (SLE) and occurs at an earlier age. The lupus-related factors that account for this increased risk are likely numerous and related to the factors described in this article. Identifying of at-risk subjects and increasing the understanding of pathogenesis of ATH in SLE is critical for improving the quality of care and improving mortality in this vulnerable population.
Keywords:
Atherosclerosis; Cardiovascular diseases; Cytokine; Proinflammatory lipids; Systemic lupus erythematosus.
Copyright © 2014 Elsevier Inc. All rights reserved.
MeSH terms
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Age Factors
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Atherosclerosis* / complications
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Atherosclerosis* / epidemiology
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Atherosclerosis* / metabolism
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Atherosclerosis* / prevention & control
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Biomarkers / metabolism
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Cardiovascular Diseases* / epidemiology
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Cardiovascular Diseases* / etiology
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Cardiovascular Diseases* / prevention & control
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Cytokines / metabolism*
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Disease Management
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Humans
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Lipid Metabolism*
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Lupus Erythematosus, Systemic* / complications
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Lupus Erythematosus, Systemic* / epidemiology
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Lupus Erythematosus, Systemic* / metabolism
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Lupus Erythematosus, Systemic* / therapy
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Outcome Assessment, Health Care
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Prevalence
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Risk Assessment / methods
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Risk Factors