Omentin on a four-pronged fork: another reason why obesity erodes cardiovascular survival

Heart Lung Circ. 2014 Sep;23(9):791-3. doi: 10.1016/j.hlc.2014.06.012. Epub 2014 Jun 28.

Abstract

Adipose tissue is now acknowledged as not just an energy storage tissue, but also as an endocrine organ that produces bioactive adipokines. Omentin is an adipokine that is gaining interest due to reports of reduced circulating plasma levels in obesity and blood vessel diseases. An emerging cardioprotective role for omentin is discussed.

Keywords: Adipokines; Cardioprotection; Diabetes; Metabolic syndrome; Obesity; Omentin.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / metabolism*
  • Animals
  • Cytokines / blood*
  • Cytokines / therapeutic use*
  • GPI-Linked Proteins / blood
  • GPI-Linked Proteins / therapeutic use
  • Humans
  • Lectins / blood*
  • Lectins / therapeutic use*
  • Myocardial Reperfusion Injury / blood
  • Myocardial Reperfusion Injury / prevention & control*
  • Obesity / blood*
  • Survival Rate

Substances

  • Cytokines
  • GPI-Linked Proteins
  • ITLN1 protein, human
  • Lectins