Use of the 2-μm continuous wave thulium laser for the resection of oral squamous cell carcinomas does not impair pathological assessment

Lasers Surg Med. 2014 Oct;46(8):608-13. doi: 10.1002/lsm.22270. Epub 2014 Aug 25.

Abstract

Background and objective: Current resection modalities for oral squamous cell carcinomas (OSCC) vary from cold steel over CO2 laser to monopolar electro-surgery (MO). We compared thulium laser (TL) as a new modality with MO with regards to pathological assessment.

Study design/materials and methods: Forty-two patients who were treated for OSCC by either TL or MO were included. All resected specimens were assessed with special attention to margin interpretation and thermal damage.

Results: Depth of thermal damage ranged from 1.0 to 3.5 mm in the TL group compared to 1.0-4.0 mm in the MO group without interfering with the pathological assessment. The percentage of positive margin resections was three times higher in the MO group compared with the TL group.

Conclusions: This study shows resections done by TL do not impair pathological assessment when compared to MO resections.

Keywords: electrosurgery; laser therapy; oral neoplasm; pathology; thulium.

MeSH terms

  • Aged
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery*
  • Female
  • Humans
  • Laser Therapy / methods*
  • Male
  • Middle Aged
  • Mouth Neoplasms / pathology
  • Mouth Neoplasms / surgery*
  • Neck Dissection
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Risk Factors
  • Thulium
  • Treatment Outcome

Substances

  • Thulium