Diagnosis and management of urinary tract infection and vesicoureteral reflux in the neonate

Rossana Baracco; Tej K Mattoo

doi:10.1016/j.clp.2014.05.011

Diagnosis and management of urinary tract infection and vesicoureteral reflux in the neonate

Clin Perinatol. 2014 Sep;41(3):633-42. doi: 10.1016/j.clp.2014.05.011. Epub 2014 Jul 18.

Authors

Rossana Baracco¹, Tej K Mattoo²

Affiliations

¹ Division of Pediatric Nephrology, Children's Hospital of Michigan, Wayne State University, 3901 Beaubien Boulevard, Detroit, MI 48201, USA.
² Division of Pediatric Nephrology, Children's Hospital of Michigan, Wayne State University, 3901 Beaubien Boulevard, Detroit, MI 48201, USA. Electronic address: tmattoo@med.wayne.edu.

PMID: 25155732
DOI: 10.1016/j.clp.2014.05.011

Abstract

Urinary tract infection (UTI) is the most common bacterial infection in febrile newborns, particularly those born prematurely and with a low birth weight. Vesicoureteral reflux (VUR) predisposes to UTI and renal scarring. Half of neonates with UTI may have only low-grade fever or no fever. Jaundice in the absence of any other symptoms or signs may be the only clinical manifestation of UTI in neonates. The urinalysis may be negative in a significant number of neonates with UTI. Newborns with UTI have a high incidence of congenital anomalies of kidney and urinary tract anomalies, and hence should undergo renal imaging.

Keywords: Diagnosis; Investigations; Neonates; UTI; Urinary tract infection; VUR; Vesicoureteral reflux.

Publication types

Review

MeSH terms

Disease Management
Global Health
Humans
Incidence
Infant, Newborn
Urinary Tract Infections* / diagnosis
Urinary Tract Infections* / epidemiology
Urinary Tract Infections* / therapy
Vesico-Ureteral Reflux* / diagnosis
Vesico-Ureteral Reflux* / epidemiology
Vesico-Ureteral Reflux* / therapy