Medication-induced Takotsubo Cardiomyopathy presenting with cardiogenic shock-utility of extracorporeal membrane oxygenation (ECMO): case report and review of the literature

Cardiovasc Revasc Med. 2015 Jan-Feb;16(1):47-51. doi: 10.1016/j.carrev.2014.07.004. Epub 2014 Jul 31.

Abstract

Takotsubo cardiomyopathy (TTC) is a transient condition that affects the myocardium and is seen mostly in post-menopausal women secondary to an emotional or physical stressor; however, certain drugs have been described as cause of this syndrome. We report the case of a young female with medication--induced TTC, who presented with cardiogenic shock as initial manifestation, treated successfully with extracorporeal membrane oxygenation (ECMO). To our knowledge, this is the first case in the literature describing the use of ECMO in cardiogenic shock due to medication-induced TTC.

Keywords: ECMO; Takotsubo cardiomyopathy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Diphenhydramine / poisoning*
  • Electrocardiography
  • Extracorporeal Membrane Oxygenation*
  • Female
  • Hemodynamics / drug effects
  • Humans
  • Ibuprofen / poisoning*
  • Recovery of Function
  • Shock, Cardiogenic / chemically induced
  • Shock, Cardiogenic / diagnosis
  • Shock, Cardiogenic / physiopathology
  • Shock, Cardiogenic / therapy*
  • Takotsubo Cardiomyopathy / chemically induced
  • Takotsubo Cardiomyopathy / diagnosis
  • Takotsubo Cardiomyopathy / physiopathology
  • Takotsubo Cardiomyopathy / therapy*
  • Time Factors
  • Treatment Outcome
  • Ventricular Function, Left / drug effects

Substances

  • Diphenhydramine
  • Ibuprofen