Osteomyelitis caused by Burkholderia pseudomallei: relapse six years after pulmonary infection

Clin Lab. 2014;60(9):1565-7. doi: 10.7754/clin.lab.2014.131222.

Abstract

Background: Burkholderia pseudomallei is highly endemic in Southeast Asia, whereas in Europe usually only few imported cases of melioidosis occur.

Case report: In 2006, a 52-year-old male patient had been admitted to hospital with pneumonia after returning from a trip to Thailand. A blood culture isolate had been identified as Pseudomonas fluorescens and the patient had been treated with Piperacillin according to the antibiogram. Six years later the patient developed osteomyelitis of the leg and Burkholderia pseudomallei was identified as the causative agent.

Conclusions: Misidentification of the cultural isolate in 2006 had led to inadequate therapy and to an unusually late relapse of melioidosis six years later.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacteriological Techniques
  • Burkholderia pseudomallei / isolation & purification*
  • Diagnostic Errors
  • Humans
  • Male
  • Melioidosis / complications
  • Melioidosis / diagnosis
  • Melioidosis / drug therapy
  • Melioidosis / microbiology*
  • Middle Aged
  • Osteomyelitis / diagnosis
  • Osteomyelitis / drug therapy
  • Osteomyelitis / microbiology*
  • Pneumonia, Bacterial / complications
  • Pneumonia, Bacterial / diagnosis
  • Pneumonia, Bacterial / drug therapy
  • Pneumonia, Bacterial / microbiology*
  • Predictive Value of Tests
  • Recurrence
  • Time Factors
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents