Up to date concepts about Von Willebrand disease and the diagnose of this hemostatic disorder

J Med Life. 2014 Sep 15;7(3):327-34. Epub 2014 Sep 25.

Abstract

The authors review the current data in literature regarding the recent knowledge about hemostase, coagulation and clinical and laboratory diagnostic algorithms of hemostatic disorders. They also present the pathological classification of bleeding disorders - the basis to clinical approach of these diseases.

Keywords: diagnostic approach; hemostase; hemostatic disorders.

Publication types

  • Review

MeSH terms

  • Arginine / analogs & derivatives
  • Gene Components
  • Hemostasis / drug effects
  • Hemostasis / physiology*
  • Humans
  • Models, Biological*
  • Pipecolic Acids
  • Platelet Adhesiveness / physiology
  • Platelet Aggregation / physiology
  • Platelet Aggregation Inhibitors / pharmacology*
  • Sulfonamides
  • von Willebrand Diseases / classification*
  • von Willebrand Diseases / diagnosis*
  • von Willebrand Diseases / physiopathology*
  • von Willebrand Factor / genetics
  • von Willebrand Factor / metabolism*

Substances

  • Pipecolic Acids
  • Platelet Aggregation Inhibitors
  • Sulfonamides
  • von Willebrand Factor
  • Arginine
  • argatroban