Imaging necrotic myocardium: detection with 99mTc-pyrophosphate and radiolabeled antimyosin

Cardiol Clin. 1989 Aug;7(3):577-88.

Abstract

The major value of hot-spot imaging of the myocardium is its ability to define areas of necrosis rather than areas of diminished blood flow or cellular function. Applications of hot-spot imaging include the diagnosis and quantitation of myocardial infarction, myocarditis, and cardiac transplant rejection. The two agents in clinical use, 99mTc-Pyrophosphate and radiolabeled antimyosin, are discussed.

Publication types

  • Review

MeSH terms

  • Animals
  • Antibodies
  • Coronary Disease / diagnostic imaging*
  • Diphosphates
  • Graft Rejection*
  • Heart Transplantation*
  • Humans
  • Myocardial Infarction / diagnostic imaging
  • Myocarditis / diagnostic imaging*
  • Myocardium / pathology*
  • Myosins / immunology
  • Necrosis
  • Postoperative Complications / diagnostic imaging*
  • Radionuclide Imaging
  • Technetium
  • Technetium Tc 99m Pyrophosphate

Substances

  • Antibodies
  • Diphosphates
  • Technetium Tc 99m Pyrophosphate
  • Technetium
  • Myosins