The Yield of Neuroimaging in Children Presenting to the Emergency Department With Acute Ataxia in the Post-Varicella Vaccine Era

J Child Neurol. 2015 Sep;30(10):1333-9. doi: 10.1177/0883073814561300. Epub 2014 Dec 22.

Abstract

To determine the yield of neuroimaging in children presenting to the emergency department with acute ataxia in the post-varicella vaccine era, we conducted a cross-sectional study between 1995 and 2013 at a single pediatric tertiary care center. We included children aged 1-18 years evaluated for acute ataxia of <7 days' duration. The main outcome was clinically urgent intracranial pathology defined as a radiologic finding that changed initial management. We identified 364 children, among whom neuroimaging was obtained in 284 (78%). Forty-two children had clinically urgent intracranial pathology (13%, 95% confidence interval 9%-17%); tumors and acute disseminated encephalomyelitis were the leading findings. Age ≤3 years and symptoms ≤3 days of duration were predictors of low risk (0.7%, 95% confidence interval 0%-4.4%). In conclusion, neuroimaging may be indicated for most patients presenting with acute ataxia. Neuroimaging may be deferred in younger children with short duration of symptoms contingent on close follow-up.

Keywords: ataxia; emergency department; imaging.

MeSH terms

  • Acute Disease
  • Adolescent
  • Age Factors
  • Ambulatory Care*
  • Ataxia / diagnosis
  • Ataxia / pathology*
  • Ataxia / therapy*
  • Brain / pathology*
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Emergency Service, Hospital
  • Female
  • Humans
  • Infant
  • Male
  • Neuroimaging*
  • Risk
  • Time Factors