Disseminated penicilliosis marneffei in immunocompetent patients: a report of two cases

Feng Ye; Qun Luo; Ying Zhou; Jiaxing Xie; Qingsi Zeng; Guoqin Chen; Danhong Su; Rongchang Chen

doi:10.4103/0255-0857.148433

Disseminated penicilliosis marneffei in immunocompetent patients: a report of two cases

Indian J Med Microbiol. 2015 Jan-Mar;33(1):161-5. doi: 10.4103/0255-0857.148433.

Authors

Feng Ye, Qun Luo, Ying Zhou, Jiaxing Xie, Qingsi Zeng, Guoqin Chen, Danhong Su, Rongchang Chen¹

Affiliation

¹ Department of Respiratory Medicine Guangzhou Institute of Respiratory Diseases , State Key Laboratory of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China, .

PMID: 25560026
DOI: 10.4103/0255-0857.148433

Abstract

Disseminated penicilliosis marneffei is rarely seen in immunocompetent persons. We report here two cases of disseminated penicilliosis marneffei in immunocompetent hosts. Penicillium marneffei disseminated to the brain in one patient and to the bone marrow in the other patient. Both patients received amphotericin B liposome. The cases illustrate the importance of considering penicilliosis marneffei as causes of systemic infections in immunocompetent patients.

Publication types

Case Reports

MeSH terms

Adult
Amphotericin B / therapeutic use
Antifungal Agents / therapeutic use
Bone Marrow / microbiology
Bone Marrow / pathology*
Brain / microbiology
Brain / pathology*
Bronchoscopy
Head / diagnostic imaging
Histocytochemistry
Humans
Magnetic Resonance Imaging
Male
Microbiological Techniques
Microscopy
Mycoses / diagnosis*
Mycoses / microbiology
Mycoses / pathology*
Penicillium / isolation & purification*
Radiography, Thoracic
Tomography, X-Ray Computed
Trachea / pathology
Treatment Outcome

Substances

Antifungal Agents
liposomal amphotericin B
Amphotericin B