Abstract
The so-called drug pipeline is not really about drugs and not much like a pipeline. It is really about the production and dissemination of information, and it is much more like a web. The misunderstanding leads to a poor understanding of what's wrong with clinical translation and how it can be improved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / administration & dosage
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Antineoplastic Agents / adverse effects
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Antineoplastic Agents / pharmacology
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Bioethical Issues*
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Clinical Trials as Topic* / methods
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Clinical Trials as Topic* / standards
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Clinical Trials as Topic* / trends
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Drug Approval*
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Drugs, Investigational*
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Humans
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Indoles / administration & dosage
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Indoles / adverse effects
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Indoles / pharmacology
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Information Dissemination* / ethics
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Models, Theoretical*
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Off-Label Use*
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Pyrroles / administration & dosage
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Pyrroles / adverse effects
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Pyrroles / pharmacology
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Research Design
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Sunitinib
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Translational Research, Biomedical* / ethics
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Translational Research, Biomedical* / methods
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Translational Research, Biomedical* / organization & administration
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Translational Research, Biomedical* / standards
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Translational Research, Biomedical* / trends
Substances
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Antineoplastic Agents
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Drugs, Investigational
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Indoles
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Pyrroles
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Sunitinib