Paliperidone palmitate for refractory and clozapine-resistant schizophrenia

João Paulo Maia-de-Oliveira; Emerson Arcoverde Nunes; Juliana Mayumi Ushirohira; João Paulo Machado-de-Sousa; Rodrigo Affosenca Bressan; Jaime Eduardo Cecílio Hallak

doi:10.1176/appi.neuropsych.13120374

Paliperidone palmitate for refractory and clozapine-resistant schizophrenia

J Neuropsychiatry Clin Neurosci. 2015 Winter;27(1):e14-6. doi: 10.1176/appi.neuropsych.13120374. Epub 2014 Dec 12.

Authors

João Paulo Maia-de-Oliveira¹, Emerson Arcoverde Nunes, Juliana Mayumi Ushirohira, João Paulo Machado-de-Sousa, Rodrigo Affosenca Bressan, Jaime Eduardo Cecílio Hallak

Affiliation

¹ From the Hospital das Clínicas, Monte Alegre, Ribeirão Preto, São Paulo, Brazil; the University of São Paulo; the Dept. of Psychiatry, Federal University of São Paulo; and the Dept. of Neuroscience and Behavior, School of Medicine of Ribeirão Preto, São Paulo, Brazil.

PMID: 25716490
DOI: 10.1176/appi.neuropsych.13120374

Abstract

This is a report on two cases of refractory schizophrenia and two cases of clozapine-resistant schizophrenia successful treated with paliperidone palmitate. To the authors' knowledge, this is the first report of the successful use of paliperidone palmitate in such patients.

Publication types

Case Reports

MeSH terms

Adult
Antipsychotic Agents / therapeutic use*
Clozapine / adverse effects*
Female
Humans
Isoxazoles / therapeutic use*
Male
Paliperidone Palmitate
Palmitates / therapeutic use*
Schizophrenia / drug therapy*
Young Adult

Substances

Antipsychotic Agents
Isoxazoles
Palmitates
Clozapine
Paliperidone Palmitate