Abstract
Vaccination is the best method for the prevention and control of influenza. Vaccination can reduce illness and lessen severity of infection. This review focuses on how currently licensed influenza vaccines are generated in the U.S., why the biology of influenza poses vaccine challenges, and vaccine approaches on the horizon that address these challenges.
Copyright © 2015 Elsevier Inc. All rights reserved.
Publication types
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Research Support, N.I.H., Intramural
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Review
MeSH terms
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Antigens, Viral / genetics
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Antigens, Viral / immunology*
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Humans
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Influenza Vaccines / immunology*
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Influenza Vaccines / isolation & purification
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Influenza, Human / prevention & control*
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Mutation*
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Orthomyxoviridae / genetics
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Orthomyxoviridae / immunology*
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Orthomyxoviridae / physiology
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Reassortant Viruses / genetics
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Reassortant Viruses / immunology*
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Technology, Pharmaceutical / methods*
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Technology, Pharmaceutical / trends
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United States
Substances
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Antigens, Viral
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Influenza Vaccines