Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies

Chem Rev. 2015 May 13;115(9):3518-63. doi: 10.1021/cr500638n. Epub 2015 Mar 19.

Abstract

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alzheimer Disease* / genetics
  • Alzheimer Disease* / metabolism
  • Alzheimer Disease* / pathology
  • Amino Acid Sequence
  • Amyloid beta-Peptides* / antagonists & inhibitors
  • Amyloid beta-Peptides* / chemistry
  • Amyloid beta-Peptides* / genetics
  • Amyloid beta-Peptides* / metabolism
  • Animals
  • Cell Membrane / metabolism
  • Computer Simulation*
  • Humans
  • Molecular Sequence Data
  • Protein Multimerization
  • Water / chemistry

Substances

  • Amyloid beta-Peptides
  • Water