Abstract
In an extensive study involving unification of secondary structure prediction methods to predict peptide backbone angles, folding simulations, and interactive graphics we have calculated conformations for a 160 residue p28sis protein fragment. We demonstrate that the state of the art is sufficient to aid artificial vaccine design.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Antigens, Viral
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Computers
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Epitopes
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Genes, Viral
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Humans
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Models, Molecular
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Oncogene Proteins v-sis
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Oncogenes*
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Platelet-Derived Growth Factor / genetics*
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Protein Conformation
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Sarcoma Virus, Woolly Monkey / genetics
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Viral Proteins / immunology*
Substances
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Antigens, Viral
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Epitopes
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Oncogene Proteins v-sis
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Platelet-Derived Growth Factor
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Viral Proteins