Clinical practice of platelet transfusions in haemato-oncology

Vox Sang. 2015 Jul;109(1):91-4. doi: 10.1111/vox.12254. Epub 2015 Mar 31.

Abstract

Platelets are prophylactically transfused to patients receiving myeloablative chemotherapy. The trigger can be adapted if a patient has risk factors for bleeding. We performed an international survey to quantify differences in transfusion policies. While platelet counts are most important, bleeding, fever, use of anticoagulants and invasive procedures also determine transfusion strategies. The largest variation of triggers was observed for lumbar punctures and removal of central venous catheters.

Keywords: guidelines; survey; transfusion policy; triggers.

MeSH terms

  • Adult
  • Aged
  • Anticoagulants / therapeutic use
  • Fever / etiology
  • Guidelines as Topic
  • Hematologic Neoplasms / pathology
  • Hemorrhage / prevention & control
  • Humans
  • Middle Aged
  • Platelet Count
  • Platelet Transfusion / adverse effects*
  • Risk Factors
  • Surveys and Questionnaires
  • Thrombocytopenia / prevention & control

Substances

  • Anticoagulants