Symptomatic venous thromboembolism following circular frame treatment for tibial fractures

Injury. 2015;46(6):1108-11. doi: 10.1016/j.injury.2015.04.003. Epub 2015 Apr 15.

Abstract

Introduction: Venous thromboembolism (VTE) is a significant cause of morbidity and mortality following tibial fractures. The risk is as high as 77% without prophylaxis and around 10% with prophylaxis. Within the current literature there are no figures reported specifically for those individuals treated with circular frames. Our aim was to evaluate the VTE incidence within a single surgeon series and to evaluate potential risk factors.

Methods: We retrospectively reviewed our consecutive single surgeon series of 177 patients admitted to a major trauma unit with tibial fractures. All patients received standardised care, including chemical thromboprophylaxis within 24h of injury until independent mobility was achieved. We comprehensively reviewed our prospective database and medical records looking at demographics and potential risk factors.

Results: Seven patients (4.0% ± 2.87%) developed symptomatic VTE during the course of frame treatment; three deep vein thrombosis (DVTs) and four pulmonary embolisms (PEs). Those with a VTE event had significantly increased body mass index (BMI) (p = 0.01) when compared to those without symptomatic VTE. No differences (p > 0.05) were observed between the groups in age, gender, smoking status, fracture type (anatomical allocation or open/closed), delay to frame treatment, weight bearing status post-frame, inpatient stay or total duration of frame treatment.

Conclusion: This study suggests that increased BMI is a statistically significant risk factor for VTE, as reported in current literature. In addition, we calculated the true risk of VTE following circular frame treatment for tibial fracture in our series is from 1.13% to 6.87%, which is at least comparable to other forms of treatment.

Keywords: Deep vein thrombosis DVT; External fixation; Ilizarov; Incidence; Pulmonary embolism PE; Taylor spatial frame TSF; Tibial fracture; Venous thromboembolism VTE.

Publication types

  • Review

MeSH terms

  • Body Mass Index
  • Chemoprevention / methods
  • Fracture Fixation / adverse effects*
  • Humans
  • Incidence
  • Obesity / complications*
  • Retrospective Studies
  • Risk Factors
  • Tibial Fractures / complications*
  • Tibial Fractures / surgery
  • Treatment Outcome
  • United Kingdom / epidemiology
  • Venous Thromboembolism / etiology*
  • Venous Thromboembolism / prevention & control