Advances in diffusion-weighted imaging

Lorenzo Mannelli; Stephanie Nougaret; Hebert A Vargas; Richard K G Do

doi:10.1016/j.rcl.2015.01.002

Advances in diffusion-weighted imaging

Radiol Clin North Am. 2015 May;53(3):569-81. doi: 10.1016/j.rcl.2015.01.002.

Authors

Lorenzo Mannelli¹, Stephanie Nougaret², Hebert A Vargas¹, Richard K G Do³

Affiliations

¹ Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
² Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; St Eloi Hospital, CHU Montpellier, Montpellier, France.
³ Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. Electronic address: dok@mskcc.org.

Abstract

Diffusion-weighted imaging (DWI) has become a routine component of clinical MR imaging. Its unique soft tissue contrast mechanism exploits differences in the motion of water molecules in vivo at a biologically meaningful scale. The clinical potential of DWI in lesion detection, characterization, and response assessment has been explored. This review briefly covers basic principles of DWI and introduces advances, specifically for abdominopelvic organs.

Keywords: Apparent diffusion coefficient; Diffusion-weighted imaging; IVIM; MR imaging; Reproducibility.

Publication types

Review

MeSH terms

Diffusion Magnetic Resonance Imaging / methods*
Diffusion Magnetic Resonance Imaging / trends
Humans
Liver Neoplasms / diagnosis
Male
Pancreatic Neoplasms / diagnosis
Prostatic Neoplasms / diagnosis
Rectal Neoplasms / diagnosis

Grants and funding

P30 CA008748/CA/NCI NIH HHS/United States