Bacteremic meningitis caused by Parvimonas micra in an immunocompetent host

Anaerobe. 2015 Aug:34:161-3. doi: 10.1016/j.anaerobe.2015.05.004. Epub 2015 May 12.

Abstract

A 61-year-old man with chronic hepatitis B and dyslipidemia visited the emergency department with a fever and severe headache. He was diagnosed with bacterial meningitis after a lumbar puncture, and blood culture revealed Parvimonas micra bacteremia. Although he had a history of extraction of a molar two weeks before symptom onset, there was no evidence of abscess formation on physical examination or imaging studies. He was successfully treated with oral metronidazole for 12 days after 9 days of treatment with IV ceftriaxone and vancomcycin. This is the first report of primary bacterial meningitis caused by this organism, which indicates that this organism is capable of being a bacterial meningitis pathogen.

Keywords: Meningitis; Parvimonas micra.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / complications
  • Bacteremia / diagnosis*
  • Bacteremia / microbiology
  • Bacteremia / pathology*
  • Bacteria, Anaerobic / classification
  • Bacteria, Anaerobic / isolation & purification
  • Ceftriaxone / therapeutic use
  • Dyslipidemias / complications
  • Firmicutes / classification
  • Firmicutes / isolation & purification*
  • Gram-Positive Bacterial Infections / complications
  • Gram-Positive Bacterial Infections / diagnosis*
  • Gram-Positive Bacterial Infections / microbiology
  • Gram-Positive Bacterial Infections / pathology*
  • Hepatitis B, Chronic / complications
  • Humans
  • Male
  • Meningitis, Bacterial / complications
  • Meningitis, Bacterial / diagnosis*
  • Meningitis, Bacterial / microbiology
  • Meningitis, Bacterial / pathology*
  • Metronidazole / therapeutic use
  • Middle Aged
  • Treatment Outcome
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Metronidazole
  • Vancomycin
  • Ceftriaxone