Does lactate account for all of the increase in anion gap in cases of metformin-induced lactic acidosis?

Clin Exp Nephrol. 2015 Dec;19(6):1210-1. doi: 10.1007/s10157-015-1124-0. Epub 2015 May 16.

Authors

Shafie Makehei¹, Ramin Sam²

Affiliations

¹ The Division of Nephrology, San Francisco General Hospital, The University of California-San Francisco, 1001 Potrero Ave, Building 100, Rm 342, San Francisco, CA, 94110-1341, USA.
² The Division of Nephrology, San Francisco General Hospital, The University of California-San Francisco, 1001 Potrero Ave, Building 100, Rm 342, San Francisco, CA, 94110-1341, USA. Ramin.Sam@ucsf.edu.

PMID: 25982073
DOI: 10.1007/s10157-015-1124-0

No abstract available

Keywords: Anion gap; Lactic acidosis; Metformin; Unmeasured anion.

Publication types

Letter

MeSH terms

Acid-Base Equilibrium
Acidosis, Lactic / chemically induced*
Acidosis, Lactic / metabolism*
Humans
Hypoglycemic Agents / adverse effects*
Lactic Acid / metabolism*
Metformin / adverse effects*
Shock, Septic / metabolism

Substances

Hypoglycemic Agents
Lactic Acid
Metformin