[HELLP syndrome]

Ginecol Obstet Mex. 2015 Jan;83(1):48-57.
[Article in Spanish]

Abstract

Hypertensive disorders of pregnancy are one of the most common complications of pregnancy, but one of the most serious expressions of this pathology is HELLP syndrome. The HELLP syndrome is characterized by the presence of hypertension disorder more a triad: microangiopathic hemolysis, elevated liver enzymes and low platelet count. Patient with HELLP syndrome is associated with increased maternal risk complications such as: cerebral hemorrhage, retinal detachment, hematoma/ hepatic rupture, acute renal failure, disseminated intravascular coagulation, placental abruption and therefore a maternal death. For all these reasons it is recommended to search for findings of HELLP syndrome in patients with hypertensive disorder of pregnancy. The main clinical confusion of HELLP syndrome is acute fatty liver of pregnancy, however there are parameters that help correct identification. The presence of HELLP syndrome involves a rapid termination of pregnancy and the administration of corticosteroids does not improve maternal morbidity and mortality but may help raise the platelet count, thus decreasing the need for transfusion and shorten hospital stay. Much of the decline in maternal morbidity and mortality associated with hypertensive disorders of pregnancy is in proper diagnosis and effective management of HELLP syndrome.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Female
  • Glucocorticoids / therapeutic use*
  • HELLP Syndrome / diagnosis
  • HELLP Syndrome / physiopathology*
  • HELLP Syndrome / therapy
  • Humans
  • Maternal Mortality*
  • Platelet Count
  • Pregnancy

Substances

  • Glucocorticoids