Bioresorbable vascular scaffold implantation for the treatment of coronary in-stent restenosis: results from a multicenter Italian experience

Int J Cardiol. 2015 Nov 15:199:366-72. doi: 10.1016/j.ijcard.2015.07.002. Epub 2015 Jul 11.

Abstract

This multicenter experience sought to investigate the feasibility and safety of BVS for the treatment of ISR. From April 2012 to June 2014, a total of 315 patients (334 lesions) underwent PCI for ISR at the participating centers. Of those, 83 patients (90 lesions) received BVS. Procedural success was achieved in all patients. At a median of 7 (IQR 3-18) months follow-up, MACCE rate was 12%, TLR 7.7%, while one (1.1%) definite BVS-in-stent thrombosis was reported. The results of this multicenter experience suggest that BVS implantation for the treatment of coronary ISR is technically feasible and associated with favorable mid-term clinical results. These data could be considered hypothesis generating for a future randomized clinical trial.

Keywords: BVS; DES; Restenosis; Stent.

Publication types

  • Multicenter Study

MeSH terms

  • Absorbable Implants*
  • Aged
  • Aged, 80 and over
  • Angioplasty, Balloon, Coronary / methods
  • Blood Vessel Prosthesis Implantation / methods*
  • Cohort Studies
  • Coronary Angiography / methods
  • Coronary Restenosis / surgery
  • Coronary Restenosis / therapy*
  • Drug-Eluting Stents*
  • Female
  • Follow-Up Studies
  • Humans
  • Italy
  • Male
  • Middle Aged
  • Percutaneous Coronary Intervention / methods
  • Prospective Studies
  • Stents*
  • Treatment Outcome