Infection-associated non-Hodgkin lymphomas

F Suarez; M Lecuit

doi:10.1016/j.cmi.2015.07.020

Infection-associated non-Hodgkin lymphomas

Clin Microbiol Infect. 2015 Nov;21(11):991-7. doi: 10.1016/j.cmi.2015.07.020. Epub 2015 Aug 4.

Authors

F Suarez¹, M Lecuit²

Affiliations

¹ Paris Descartes University, Department of Haematology, Necker-Enfants Malades University Hospital, Institut Imagine, Paris, France; Laboratory of Molecular Mechanisms of Haematologic al Disorders and Therapeutic Implications, Institut Imagine, INSERM UMR 1163 and CNRS ERL 8254, Paris, France. Electronic address: felipe.suarez@aphp.fr.
² Biology of Infection Unit, Institut Pasteur, Paris, France; Inserm U1117, Paris, France; Paris Descartes University, Department of Infectious Diseases and Tropical Medicine, Necker-Enfants Malades Hospital, Institut Imagine, Paris, France. Electronic address: marc.lecuit@pasteur.fr.

PMID: 26253291
DOI: 10.1016/j.cmi.2015.07.020

Abstract

Non-Hodgkin lymphomas (NHLs) are malignant proliferations of lymphoid cells. Lymphoid cells proliferate in a physiological manner in response to antigen-dependent and antigen-independent signals. Some lymphotropic viruses, such as Epstein-Barr virus and human T-lymphotropic virus 1, as well as pathogens leading to chronic antigenic stimulation (such as Helicobacter pylori and hepatitis C virus), are associated with NHL. We review here some of the pathophysiological features of infection-associated NHL.

Keywords: EBV; HCV; Helicobacter; infection; lymphoma.

Publication types

Review

MeSH terms

Communicable Diseases / complications*
Helicobacter pylori / immunology
Helicobacter pylori / physiology
Hepacivirus / immunology
Hepacivirus / physiology
Herpesvirus 4, Human / immunology
Herpesvirus 4, Human / physiology
Human T-lymphotropic virus 1 / immunology
Human T-lymphotropic virus 1 / physiology
Humans
Lymphoma, Non-Hodgkin / epidemiology*
Lymphoma, Non-Hodgkin / microbiology
Lymphoma, Non-Hodgkin / pathology*
Lymphoma, Non-Hodgkin / virology