Secondary Hyperparathyroidism With "Superscan-Like" Hypermetabolic FDG PET/CT Pattern

Clin Nucl Med. 2015 Nov;40(11):888-9. doi: 10.1097/RLU.0000000000000952.

Abstract

A 26-year-old man with chronic terminal renal insufficiency under dialysis was referred in our institution for a checkup before kidney transplantation to ensure the absence of malignant neoplasm. The patient had a biological secondary hyperparathyroidism with highly elevated serum parathormon, and treatment with parathyroid surgery was planned before the kidney transplant. Whole-body FDG PET/CT showed no apparent malignant neoplasm, but increased metabolism of the 4 parathyroid gland and the other pitfalls of advanced secondary hyperparathyroidism on chronic renal insufficiency: pseudotumoral calcification in soft tissues, diffuse hypermetabolic bone dystrophy, and osteolytic lesion of pelvic and peripheral skeleton corresponding to brown tumors.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone and Bones / diagnostic imaging
  • Calcinosis / complications
  • Calcinosis / diagnostic imaging*
  • Fluorodeoxyglucose F18*
  • Humans
  • Hyperparathyroidism, Secondary / complications
  • Hyperparathyroidism, Secondary / diagnostic imaging*
  • Male
  • Multimodal Imaging
  • Parathyroid Glands / diagnostic imaging
  • Positron-Emission Tomography*
  • Radiopharmaceuticals
  • Renal Insufficiency / complications
  • Renal Insufficiency / diagnostic imaging*
  • Tomography, X-Ray Computed*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18