A frazzled man in his early thirties presented with a 4 year long history of frequent progressive airway obstruction. He had undergone two open laryngeal surgeries and multiple endolaryngeal procedures for excision of a subglottic lesion which recurred. Each time the histopathology showed a different entity ranging from hemangioma and fibrihystiocytic lesion and spindle cell carcinoma. Finally the case was proven to be an intermediate grade sarcoma of neurogenic origin. He underwent widefield laryngectomy with placement of Provox-2 prosthesis followed by radiotherapy. Five years following surgery, he is progressing well. The case is being reported for its rarity and also for the histogenetic problems associated with this group of lesions. Authors found only one other case of laryngeal neurofibrosarcoma that was reported 29 years back [3].
Keywords: Larynx; Neurofibrosarcoma; Subglottis.