Alterations in bone marrow metabolism are an early and consistent feature during the development of MGUS and multiple myeloma

Blood Cancer J. 2015 Oct 16;5(10):e359. doi: 10.1038/bcj.2015.85.

Authors

C Ludwig¹, D S Williams¹, D B Bartlett¹, S J Essex¹, G McNee¹, J W Allwood², E Jewell², A Barkhuisen³, H Parry¹, S Anandram³, P Nicolson⁴, C Gardener⁴, F Seymour⁴, S Basu³, W B Dunn², P A H Moss¹, G Pratt^{1

4}, D A Tennant¹

Affiliations

¹ School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
² School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
³ Department of Haematology, The Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
⁴ Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Biomarkers, Tumor / analysis*
Bone Marrow / metabolism*
Bone Marrow / pathology
Humans
Magnetic Resonance Spectroscopy
Metabolome
Monoclonal Gammopathy of Undetermined Significance / metabolism*
Monoclonal Gammopathy of Undetermined Significance / pathology
Multiple Myeloma / metabolism*
Principal Component Analysis

Substances

Biomarkers, Tumor