Breast filariasis or inflammatory breast carcinoma? Reaching a diagnosis

BMJ Case Rep. 2015 Nov 13:2015:bcr2015212254. doi: 10.1136/bcr-2015-212254.

Abstract

Lymphatic filariasis is a neglected tropical disease caused by the parasite Wuchereria bancrofti. Involvement of the breast is relatively uncommon and may affect only 10% of individuals with lymphatic filariasis. We present a case of an elderly woman with breast pathology. The condition clinically appeared as a malignancy. Routine diagnostic tests including tissue histopathological studies failed to clinch a diagnosis. However, a serological test helped in identifying the pathology, which turned out to be a manifestation of breast filariasis, and aided in instituting appropriate therapy for this condition.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Axilla / parasitology*
  • Axilla / pathology
  • Biomarkers / blood
  • Biopsy, Needle
  • Breast / parasitology*
  • Breast / pathology
  • Breast Diseases / diagnosis*
  • Breast Diseases / drug therapy
  • Breast Diseases / parasitology
  • Breast Diseases / pathology
  • Diagnosis, Differential
  • Diethylcarbamazine / therapeutic use*
  • Female
  • Filariasis / diagnosis*
  • Filariasis / drug therapy
  • Filaricides / therapeutic use*
  • Humans
  • Inflammatory Breast Neoplasms / diagnosis*
  • Mammography
  • Ofloxacin / therapeutic use
  • Predictive Value of Tests
  • Serologic Tests
  • Treatment Outcome
  • Wuchereria bancrofti / isolation & purification*

Substances

  • Anti-Bacterial Agents
  • Biomarkers
  • Filaricides
  • Ofloxacin
  • Diethylcarbamazine