Dilemmas in Managing Pregnant Women With Ebola: 2 Case Reports

Séverine Caluwaerts; Tessy Fautsch; Daphne Lagrou; Michel Moreau; Alseny Modet Camara; Stephan Günther; Antonino Di Caro; Benny Borremans; Fara Raymond Koundouno; Joseph Akoi Bore; Christopher H Logue; Martin Richter; Roman Wölfel; Eeva Kuisma; Andreas Kurth; Stephen Thomas; Gillian Burkhardt; Elin Erland; Fanshen Lionetto; Patricia Lledo Weber; Olimpia de la Rosa; Hassan Macpherson; Michel Van Herp

doi:10.1093/cid/civ1024

Dilemmas in Managing Pregnant Women With Ebola: 2 Case Reports

Clin Infect Dis. 2016 Apr 1;62(7):903-905. doi: 10.1093/cid/civ1024. Epub 2015 Dec 17.

Authors

Séverine Caluwaerts^{1

2}, Tessy Fautsch¹, Daphne Lagrou¹, Michel Moreau³, Alseny Modet Camara⁴, Stephan Günther^{5

6}, Antonino Di Caro^{5

7}, Benny Borremans^{5

8}, Fara Raymond Koundouno^{5

9

10}, Joseph Akoi Bore^{5

9

10}, Christopher H Logue^{5

11}, Martin Richter^{5

12}, Roman Wölfel^{5

13}, Eeva Kuisma^{5

11}, Andreas Kurth^{5

12}, Stephen Thomas^{5

11}, Gillian Burkhardt¹⁴, Elin Erland¹⁴, Fanshen Lionetto¹⁴, Patricia Lledo Weber¹⁴, Olimpia de la Rosa¹⁴, Hassan Macpherson¹⁵, Michel Van Herp¹

Affiliations

¹ Médecins Sans Frontières, Operational Centre Brussels.
² Institute of Tropical Medicine, Antwerp.
³ Department of Emergency Medicine, Centre Hospitalier Chrétien, Liège, Belgium.
⁴ Médecins Sans Frontières, Guéckedou, Guinea.
⁵ The European Mobile Laboratory Consortium.
⁶ Bernhard Nocht Institute for Tropical Medicine, World Health Organization Collaborating Centre for Arboviruses and Hemorrhagic Fever Reference and Research, Hamburg, Germany.
⁷ National Institute for Infectious Diseases "L. Spallanzani", Rome, Italy.
⁸ Evolutionary Ecology Group, University of Antwerp, Belgium.
⁹ Laboratoire des Fièvres Hémorragiques en Guinée, Université Gamal Abdel Nasser de Conakry.
¹⁰ Institut National de Santé Publique, Conakry, Guinea.
¹¹ Public Health England, Porton Down, United Kingdom.
¹² Robert Koch Institute, Berlin.
¹³ Bundeswehr Institute of Microbiology, Munich, Germany.
¹⁴ Médecins Sans Frontières, Operational Centre Barcelona, Spain.
¹⁵ Ministry of Health and Sanitation, Freetown, Sierra Leone.

Abstract

We report 2 cases of Ebola viral disease (EVD) in pregnant women who survived, initially with intact pregnancies. Respectively 31-32 days after negativation of the maternal blood EVD-polymerase chain reaction (PCR) both patients delivered a stillborn fetus with persistent EVD-PCR amniotic fluid positivity.

Keywords: EVD; Ebola; pregnancy.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Amniotic Fluid / virology
Female
Fetal Blood / virology
Hemorrhagic Fever, Ebola*
Humans
Placenta / virology
Pregnancy
Pregnancy Complications, Infectious*
Stillbirth
Young Adult