Hemagglutinin Gene Clade 3C.2a Influenza A(H3N2) Viruses, Alachua County, Florida, USA, 2014-15

Emerg Infect Dis. 2016 Jan;22(1):121-3. doi: 10.3201/2201.151019.

Abstract

Influenza A(H3N2) strains isolated during 2014-15 in Alachua County, Florida, USA, belonged to hemagglutinin gene clade 3C.2a. High rates of influenza-like illness and confirmed influenza cases in children were associated with a decrease in estimated vaccine effectiveness. Illnesses were milder than in 2013-14; severe cases were concentrated in elderly patients with underlying diseases.

Keywords: Florida; hemagglutinin; influenza; influenza A(H3N2); respiratory infections; vaccines; viruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Florida
  • Hemagglutination Inhibition Tests / methods
  • Hemagglutinins / genetics*
  • Humans
  • Infant
  • Infant, Newborn
  • Influenza A Virus, H3N2 Subtype / genetics*
  • Influenza A Virus, H3N2 Subtype / immunology
  • Influenza Vaccines / immunology
  • Influenza, Human / immunology
  • Influenza, Human / virology*

Substances

  • Hemagglutinins
  • Influenza Vaccines

Associated data

  • GENBANK/KP126913
  • GENBANK/KP126914
  • GENBANK/KP126915
  • GENBANK/KP126916
  • GENBANK/KP126917
  • GENBANK/KP153349
  • GENBANK/KP153350
  • GENBANK/KP153351
  • GENBANK/KP153352
  • GENBANK/KP153353
  • GENBANK/KP153354
  • GENBANK/KP153355
  • GENBANK/KP153356
  • GENBANK/KP153357
  • GENBANK/KP153358