Successful management of pulmonary hemorrhage and aspergillosis in a patient with acute myeloid leukemia (AML-M3)

Hulya Gunbatar; Cengiz Demir; Erdal Kara; Ramazan Esen; Bunyamin Sertogullarindan; Selvi Asker

doi:10.1016/j.rmcr.2015.07.003

Successful management of pulmonary hemorrhage and aspergillosis in a patient with acute myeloid leukemia (AML-M3)

Respir Med Case Rep. 2015 Jul 26:16:65-8. doi: 10.1016/j.rmcr.2015.07.003. eCollection 2015.

Authors

Hulya Gunbatar¹, Cengiz Demir², Erdal Kara², Ramazan Esen², Bunyamin Sertogullarindan¹, Selvi Asker¹

Affiliations

¹ Yuzuncu Yil University Medical Faculty, Department of Pulmonary and Critical Care, Turkey.
² Yuzuncu Yil University Medical Faculty, Department of Internal Medicine, Haematology, Turkey.

Abstract

A 35-year-old man presented with a one month history of gingival bleeding. He was diagnosed with Acute Myeloid Leukemia (AML-M3). During treatment he developed alveolar hemorrhage for which he was treated with a steroid. After the steroid treatment he developed a nodule, a cavitary lesion and atelectasia in the left lung. He was treated with voriconazole. After therapy with voriconazole his lesion significantly decreased. This case illustrates the efficacy and safety of antifungal therapy with voriconazole for aspergillosis complicated by AML.

Keywords: Acute myeloid leukemia; Immunosuppression; Invasive aspergillosis; Pulmonary hemorrhage; Variconazole.

Publication types

Case Reports