Hepatitis B immune reconstitution syndrome in a patient with HIV infection

Int J STD AIDS. 2016 Oct;27(12):1126-1129. doi: 10.1177/0956462416628320. Epub 2016 Jan 13.

Abstract

South Africa has a high rate of HIV and hepatitis B co-infection. The national HIV treatment guidelines include anti-retrovirals that treat both viruses. We describe a HIV-positive patient who presented with liver histology-confirmed hepatitis B immune reconstitution inflammatory syndrome whilst on a regimen containing lamivudine and tenofovir.

Keywords: AIDS; HIV; co-infection; hepatitis B virus; immune reconstitution inflammatory syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-HIV Agents / therapeutic use
  • Antiretroviral Therapy, Highly Active
  • Coinfection / virology
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • HIV Infections / virology
  • HIV-1 / drug effects
  • Hepatitis B / complications*
  • Hepatitis B / drug therapy
  • Hepatitis B / virology
  • Hepatitis B virus / drug effects
  • Hepatitis B virus / genetics
  • Humans
  • Immune Reconstitution Inflammatory Syndrome / complications*
  • Immune Reconstitution Inflammatory Syndrome / drug therapy
  • Lamivudine / administration & dosage
  • Lamivudine / therapeutic use
  • Treatment Outcome

Substances

  • Anti-HIV Agents
  • Lamivudine