Viral haemorrhagic fever in children

Arch Dis Child. 2016 May;101(5):461-8. doi: 10.1136/archdischild-2014-307861. Epub 2016 Jan 19.

Abstract

Viral haemorrhagic fevers (VHFs) are currently at the forefront of the world's attention due to the recent Zaire ebola virus epidemic in West Africa. This epidemic has highlighted the frailty of the world's public health response mechanisms and demonstrated the potential risks to nations around the world of imported cases of epidemic diseases. While imported cases in children are less likely, the potential for such a scenario remains. It is therefore essential that paediatricians are aware of and prepared for potential imported cases of tropical diseases, VHFs being of particular importance due to their propensity to cause nosocomial spread. Examining the four families of viruses--Filoviridae, Arenaviridae, Bunyaviridae and Flaviviridae--we describe the different types of VHFs, with emphasis on differentiation from other diseases through detailed history-taking, their presentation and management from a paediatric perspective.

Keywords: Children; Ebola virus disease; Lassa fever; Marburg virus; Viral haemorrhagic fever.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Child, Preschool
  • Cross Infection / epidemiology
  • Disease Outbreaks
  • Female
  • Hemorrhagic Fevers, Viral / diagnosis*
  • Hemorrhagic Fevers, Viral / epidemiology*
  • Hemorrhagic Fevers, Viral / therapy
  • Humans
  • Infant
  • Infant, Newborn
  • Male