Immunometabolism: Metabolism fine-tunes macrophage activation

Elife. 2016 Feb 19:5:e14354. doi: 10.7554/eLife.14354.

Abstract

A signaling pathway that rewires metabolism in macrophages to trigger changes in gene expression has been identified.

Keywords: akt, acly; cell biology; immunology; immunometabolism; mTORC1; macrophage activation; macrophage metabolism; mouse.

Publication types

  • Comment

MeSH terms

  • Gene Expression
  • Humans
  • Macrophage Activation*
  • Macrophages / metabolism*
  • Proto-Oncogene Proteins c-akt / metabolism
  • Signal Transduction

Substances

  • Proto-Oncogene Proteins c-akt