MLL rearrangements impact outcome in HOXA-deregulated T-lineage acute lymphoblastic leukemia: a Children's Oncology Group Study

Leukemia. 2016 Sep;30(9):1909-12. doi: 10.1038/leu.2016.60. Epub 2016 Mar 8.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural

MeSH terms

  • Adolescent
  • Adult
  • Cell Lineage*
  • Child
  • Child, Preschool
  • Disease-Free Survival
  • Drug Resistance, Neoplasm / genetics*
  • Female
  • Gene Rearrangement
  • Histone-Lysine N-Methyltransferase / genetics*
  • Homeodomain Proteins / genetics*
  • Humans
  • Male
  • Myeloid-Lymphoid Leukemia Protein / genetics*
  • Neoplasm Recurrence, Local / genetics*
  • Neoplasm Recurrence, Local / mortality
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / mortality
  • Prognosis
  • Retrospective Studies

Substances

  • Homeodomain Proteins
  • KMT2A protein, human
  • Myeloid-Lymphoid Leukemia Protein
  • HoxA protein
  • Histone-Lysine N-Methyltransferase