Ischaemic stroke in the setting of glioblastoma: A case series and review of the literature

Neuroradiol J. 2016 Jun;29(3):155-9. doi: 10.1177/1971400916639603. Epub 2016 Mar 17.

Abstract

Ischaemic strokes are an uncommon occurrence in the setting of glioblastoma, and clinically challenging due to co-existing deficits from the tumour, but important to consider as a possible cause of clinical deterioration. Modern therapies and their associated improvements in survival may lead to a greater overall incidence. The possible underlying causes of ischaemia are multiple, and several factors may contribute in a given patient. This review discusses the causative mechanisms of ischaemic strokes in the setting of glioblastoma, with some illustrative cases.

Keywords: Glioblastoma; ischaemia; stroke.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Brain Ischemia / complications*
  • Brain Ischemia / diagnostic imaging
  • Brain Neoplasms / complications*
  • Brain Neoplasms / diagnostic imaging
  • Diffusion Magnetic Resonance Imaging
  • Female
  • Glioblastoma / complications*
  • Glioblastoma / diagnostic imaging
  • Humans
  • Male
  • Middle Aged
  • Risk Factors
  • Stroke / complications*
  • Stroke / diagnostic imaging