Spontaneous resolution of cryptogenic organizing pneumonia in pediatrics: A case report

Arch Pediatr. 2016 May;23(5):519-22. doi: 10.1016/j.arcped.2016.02.021. Epub 2016 Mar 24.

Abstract

Cryptogenic organizing pneumonia (COP) is a rare entity in childhood, particularly in previously healthy children. Moreover, the spontaneous remission of the disease is exceptional. We report on the case of a previously healthy 10-year-old girl who consulted her doctor for a 2-month history of mild pyrexia, fatigue, weight loss, and exertional dyspnea with no response to amoxicillin. A chest CT revealed bilateral, asymmetrical peribronchovascular consolidation areas predominating in the lower lobes and imaging features of COP. The bronchoalveolar lavage and the biological findings were negative. On follow-up, the girl showed clinical and radiological remission of the disease with no treatment. Our report describes an extremely rare case of spontaneously resolving COP in a child, the diagnosis being made based on the imaging pattern.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Cryptogenic Organizing Pneumonia / complications
  • Cryptogenic Organizing Pneumonia / diagnostic imaging*
  • Dyspnea / etiology
  • Female
  • Humans
  • Pediatrics*
  • Predictive Value of Tests
  • Remission, Spontaneous
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed* / methods