Epstein-Barr virus-associated iris smooth muscle tumor with epithelioid morphology in AIDS patients: a case report

Yanin Suwan; Duangnate Rojanaporn; Chaiwat Teekhasaenee; Somboon Keelawat

doi:10.2147/IMCRJ.S96837

Epstein-Barr virus-associated iris smooth muscle tumor with epithelioid morphology in AIDS patients: a case report

Int Med Case Rep J. 2016 Mar 30:9:83-6. doi: 10.2147/IMCRJ.S96837. eCollection 2016.

Authors

Yanin Suwan¹, Duangnate Rojanaporn¹, Chaiwat Teekhasaenee¹, Somboon Keelawat²

Affiliations

¹ Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
² Department of Pathology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.

Abstract

Importance: Report of an acquired immunodeficiency syndrome (AIDS) patient with Epstein-Barr virus (EBV)-associated iris smooth muscle tumor.

Observations: A 14-year-old African American female diagnosed with AIDS developed a painless iris mass in the right eye for 10 months. Iridocyclectomy was performed, and the pathology indicated EBV-associated iris smooth muscle tumor with epithelioid morphology. Immunohistochemical stains and in situ hybridization for EBV-encoded ribonucleic acid are very useful diagnostic tools for definite diagnosis. At 14-month follow-up, the patient did not have any tumor recurrence.

Conclusion: This is the case report of EBV-associated iris smooth muscle tumor in a person diagnosed with AIDS with a unique epithelioid morphologic feature.

Keywords: Epstein-Barr virus; acquired immunodeficiency syndrome (AIDS); human immunodeficiency virus (HIV); iris tumor; leiomyosarcoma; smooth muscle tumor.

Publication types

Case Reports