23-Valent Pneumococcal Polysaccharide Vaccine Uptake in the United States Air Force HIV Program

J Int Assoc Provid AIDS Care. 2016 Jul;15(4):286-90. doi: 10.1177/2325957416649667. Epub 2016 May 23.

Abstract

Streptococcus pneumoniae infection is a predominant cause of bacterial infection in HIV-infected individuals. However, reported rates of pneumococcal vaccination with 23-valent polysaccharide vaccine (PPV23) are variable. We evaluated uptake of PPV23 in patients diagnosed with HIV between 1996 and 2012 (n = 507) in the United States Air Force, a centralized HIV program with free access to care including vaccines and medications. A total of 411 (81.1%) patients received at least 1 PPV23 dose. The PPV23 vaccination within 1 year of diagnosis was greater for those diagnosed between 2004 and 2012 (n = 184, 86%) compared with 1996 to 2003 (n = 104, 56.5%; P < .001). For those with ≥6 years of follow-up, receipt of a second recommended PPV23 dose was greater for those diagnosed between 1996 and 2003 (n = 52, 57.8%) compared with 2004 to 2012 (n = 9, 28.1%; P = .004). Although first PPV23 vaccination was high in recent years, process improvement efforts are underway to overcome barriers and improve uptake of pneumococcal vaccines in our program.

Keywords: HIV; Streptococcus pneumoniae infection; pneumococcal polysaccharide vaccine.

MeSH terms

  • Adult
  • Female
  • HIV Infections / epidemiology*
  • Humans
  • Male
  • Military Medicine
  • Military Personnel / statistics & numerical data*
  • Pneumococcal Infections / prevention & control*
  • Pneumococcal Vaccines* / administration & dosage
  • Pneumococcal Vaccines* / therapeutic use
  • United States
  • Vaccination / statistics & numerical data*
  • Young Adult

Substances

  • 23-valent pneumococcal capsular polysaccharide vaccine
  • Pneumococcal Vaccines