Identification and Antifungal Susceptibility Profile of Candida guilliermondii and Candida fermentati from a Multicenter Study in China

Jing-Wei Cheng; Shu-Ying Yu; Meng Xiao; He Wang; Timothy Kudinha; Fanrong Kong; Ying-Chun Xu

doi:10.1128/JCM.00938-16

Identification and Antifungal Susceptibility Profile of Candida guilliermondii and Candida fermentati from a Multicenter Study in China

J Clin Microbiol. 2016 Aug;54(8):2187-9. doi: 10.1128/JCM.00938-16. Epub 2016 Jun 1.

Authors

Jing-Wei Cheng¹, Shu-Ying Yu¹, Meng Xiao², He Wang², Timothy Kudinha³, Fanrong Kong⁴, Ying-Chun Xu⁵

Affiliations

¹ Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
² Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
³ The Charles Sturt University, Orange, New South Wales, Australia Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead Hospital, Westmead, New South Wales, Australia.
⁴ The Charles Sturt University, Orange, New South Wales, Australia.
⁵ Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China xycpumch@139.com.

Abstract

With molecular sequencing as a gold standard, the Vitek MS, Bruker Biotyper MS, and Vitek-2 Compact systems correctly identified 92.7%, 97.0%, and 15.2% of 164 Candida guillermondii isolates, respectively, and none of 8 C. fermentati isolates. All of the isolates showed high susceptibility to echinocandins, but some C. guilliermondii isolates showed low azole susceptibility.

Publication types

Multicenter Study

MeSH terms

Adult
Aged
Antifungal Agents / pharmacology*
Candida / drug effects*
Candida / isolation & purification*
Candidiasis / microbiology*
China
Female
Humans
Male
Microbial Sensitivity Tests
Middle Aged

Substances

Antifungal Agents