Management of rib fractures in traumatic flail chest: a meta-analysis of randomised controlled trials

Bone Joint J. 2016 Aug;98-B(8):1119-25. doi: 10.1302/0301-620X.98B8.37282.

Abstract

Aims: Flail chest from a blunt injury to the thorax is associated with significant morbidity and mortality. Its management globally is predominantly non-operative; however, there are an increasing number of centres which undertake surgical stabilisation. The aim of this meta-analysis was to compare the efficacy of this approach with that of non-operative management.

Patients and methods: A systematic search of the literature was carried out to identify randomised controlled trials (RCTs) which compared the clinical outcome of patients with a traumatic flail chest treated by surgical stabilisation of any kind with that of non-operative management.

Results: Of 1273 papers identified, three RCTs reported the results of 123 patients with a flail chest. Surgical stabilisation was associated with a two thirds reduction in the incidence of pneumonia when compared with non-operative management (risk ratio 0.36, 95% confidence interval (CI) 0.15 to 0.85, p = 0.02). The duration of mechanical ventilation (mean difference -6.30 days, 95% CI -12.16 to -0.43, p = 0.04) and length of stay in an intensive care unit (mean difference -6.46 days, 95% CI 9.73 to -3.19, p = 0.0001) were significantly shorter in the operative group, as was the overall length of stay in hospital (mean difference -11.39, 95% CI -12.39 to -10.38, p < 0.0001).

Conclusion: Surgical stabilisation for a traumatic flail chest is associated with significant clinical benefits in this meta-analysis of three relatively small RCTs. Cite this article: Bone Joint J 2016;98-B:1119-25.

Keywords: Chest injury; Internal fixation; Meta-analysis; Rib fracture.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Adult
  • Female
  • Flail Chest / mortality
  • Flail Chest / therapy*
  • Fracture Fixation / methods
  • Fracture Fixation / mortality
  • Humans
  • Length of Stay
  • Male
  • Pneumonia / etiology
  • Pneumonia / mortality
  • Postoperative Complications / etiology
  • Postoperative Complications / mortality
  • Randomized Controlled Trials as Topic
  • Respiration, Artificial / mortality
  • Rib Fractures / mortality
  • Rib Fractures / therapy*
  • Treatment Outcome
  • Wounds, Nonpenetrating / mortality
  • Wounds, Nonpenetrating / therapy*