Effects of whey protein supplement in the elderly submitted to resistance training: systematic review and meta-analysis

Int J Food Sci Nutr. 2017 May;68(3):257-264. doi: 10.1080/09637486.2016.1232702. Epub 2016 Sep 21.

Abstract

Aim: We performed a systematic review to map the evidence and analyze the effect of whey protein supplementation in the elderly submitted to resistance training.

Methods: A comprehensive search on Medline, LILACS, EMBASE, and the Cochrane Library for relevant publications was conducted until August 2015. The terms used in the search were: "Resistance training"; "Whey protein"; "Elderly".

Results: A total of 632 studies were screened. Five studies were included composing a sample of 391 patients. The supplement whey protein was associated with higher total protein ingestion 9.40 (95% CI: 4.03-14.78), and with an average change in plasma leucine concentration. The supplementation was also associated with increased mixed muscle protein synthesis 1.26 (95% CI: 0.46-2.07) compared to the control group.

Conclusion: We observed an increase in total protein intake, resulting in increased concentration of leucine and mixed muscle protein fractional synthesis rate.

Keywords: Systematic review; elderly; meta-analyses; whey protein.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Aged
  • Databases, Factual
  • Dietary Supplements*
  • Humans
  • Muscle Proteins / biosynthesis
  • Muscle, Skeletal / drug effects
  • Muscle, Skeletal / metabolism
  • Randomized Controlled Trials as Topic
  • Resistance Training*
  • Whey Proteins / administration & dosage*

Substances

  • Muscle Proteins
  • Whey Proteins