Pulmonary Cryptococcoma Masquerading as Lung Cancer

J Assoc Physicians India. 2016 May;64(5):66-68.

Abstract

We report a case of pulmonary cryptococcoma, in an adult with recently detected diabetes, mimicking as lung cancer. A 45-year-old gentleman with past history of pulmonary tuberculosis presented with fever, cough with expectoration, pleuritic chest pain and hemoptysis. Chest radiograph and computed tomography revealed right lower lobe mass which significantly enhanced on contrast administration. Ultrasound guided biopsy was done which on histopathological examination showed non-necrotizing granulomas with narrow-based budding yeast cells suggestive of cryptococcosis. Detailed work-up for dissemination of infection was negative. A dramatic response to anti-fungal treatment was observed and the patient is doing fine on follow-up.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use*
  • Chest Pain / diagnostic imaging*
  • Cough / etiology
  • Cryptococcosis / diagnosis*
  • Cryptococcosis / drug therapy*
  • Cryptococcosis / pathology
  • Cryptococcus neoformans / isolation & purification*
  • Fluconazole / therapeutic use
  • Hemoptysis / etiology
  • Humans
  • Lung Diseases, Fungal / diagnosis
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed*
  • Treatment Outcome

Substances

  • Antifungal Agents
  • Amphotericin B
  • Fluconazole