Abstract
Human papillomavirus (HPV) is a common infection in kidney transplant recipients. HPV causes cervical, anal, vulvar, vaginal, penile and head and neck cancers. Kidney transplant recipients have a disproportionate burden of disease given prolonged immunosuppression. Given the long pre-invasive state of precancer lesions such as cervical intraepithelial neoplasia (CIN) and anal intraepithelial neoplasia (AIN) most HPV-cancers are preventable with screening and targeted treatment of disease. Pre-transplant vaccination of age-eligible kidney transplant recipients is otherwise ideal.
Keywords:
HPV; Pap test; anal cancer; cervical cancer; kidney transplant; vaccine.
Copyright © 2016 Elsevier Inc. All rights reserved.
MeSH terms
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Anus Neoplasms / diagnosis
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Anus Neoplasms / prevention & control
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Anus Neoplasms / therapy
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Anus Neoplasms / virology*
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Carcinoma in Situ / diagnosis
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Carcinoma in Situ / prevention & control
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Carcinoma in Situ / therapy
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Carcinoma in Situ / virology
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Early Detection of Cancer
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Female
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Graft Rejection / prevention & control*
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Humans
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Immunosuppressive Agents / adverse effects*
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Kidney Failure, Chronic / surgery*
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Kidney Transplantation*
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Male
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Papanicolaou Test
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Papillomaviridae
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Papillomavirus Infections / chemically induced*
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Papillomavirus Infections / diagnosis
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Papillomavirus Infections / prevention & control
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Papillomavirus Infections / therapy
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Papillomavirus Vaccines / therapeutic use
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Uterine Cervical Dysplasia / diagnosis
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Uterine Cervical Dysplasia / prevention & control
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Uterine Cervical Dysplasia / therapy
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Uterine Cervical Dysplasia / virology*
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Uterine Cervical Neoplasms / diagnosis
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Uterine Cervical Neoplasms / prevention & control
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Uterine Cervical Neoplasms / therapy
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Uterine Cervical Neoplasms / virology*
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Vaginal Smears
Substances
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Immunosuppressive Agents
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Papillomavirus Vaccines