Production, properties, and applications of endo-β-mannanases

Biotechnol Adv. 2017 Jan-Feb;35(1):1-19. doi: 10.1016/j.biotechadv.2016.11.001. Epub 2016 Nov 9.

Abstract

The present review provides up-to-date information on the occurrence and methodologies used for producing and purifying endo-β-mannanases and a comprehensive comparison of their biochemical properties. The amalgamation of biochemical, molecular and structural biology approaches which have been used for understanding endo-β-mannanase families, catalytic mechanism, substrate binding, non-catalytic modules, trans-glycosylation, and multi-functional enzyme complexes has been given critical attention. A separate section entailing the state-of-the-art about thermostable endo-β-mannanases, which has emerged as an exciting field of both basic and applied research, is also deliberated. The remarkable progress made by endo-β-mannanases in various industrial sectors like food, feed, detergents, biofuel and oil drilling is also emphasized.

Keywords: Biochemical properties; Endo-β-mannanase; Genetic engineering; Industrial application; Structural organization; Thermo-stability.

Publication types

  • Review

MeSH terms

  • Bacillus / enzymology
  • Enzyme Stability
  • Fungi / enzymology
  • Genetic Engineering
  • Mannans / chemistry
  • Mannans / metabolism
  • Models, Molecular
  • Plants / enzymology
  • beta-Mannosidase* / chemistry
  • beta-Mannosidase* / genetics
  • beta-Mannosidase* / metabolism

Substances

  • Mannans
  • galactoglucomannan
  • beta-Mannosidase