MitraClip Therapy for Mitral Regurgitation: Secondary Mitral Regurgitation

Ted Feldman; Arjun Mehta; Mayra Guerrero; Justin P Levisay; Michael H Salinger

doi:10.1016/j.iccl.2015.08.007

MitraClip Therapy for Mitral Regurgitation: Secondary Mitral Regurgitation

Interv Cardiol Clin. 2016 Jan;5(1):83-91. doi: 10.1016/j.iccl.2015.08.007. Epub 2015 Nov 18.

Authors

Ted Feldman¹, Arjun Mehta², Mayra Guerrero², Justin P Levisay², Michael H Salinger²

Affiliations

¹ NorthShore University HealthSystem, Evanston, IL, USA. Electronic address: tfeldman@tfeldman.org.
² NorthShore University HealthSystem, Evanston, IL, USA.

PMID: 27852484
DOI: 10.1016/j.iccl.2015.08.007

Abstract

Therapy for mitral regurgitation (MR) has been synonymous with mitral valve surgery. Operative approaches for degenerative MR repair have been associated with excellent results, with durable long term outcomes. Surgery for functional MR has been less successful. MitraClip has shown promise for functional MR, especiall in patinets who are high risk for surgery. The aggregate of nonrandomized global experience with MitraClip in functional MR has been consistent in showing improvements in symptoms and left ventricular remodeling. It remains to be seen how MitraClip therapy will compare with best medical therapy. The COAPT trial will clarify this question.

Keywords: COAPT; Functional mitral regurgitation; MitraClip; Mitral regurgitation.

Publication types

Review

MeSH terms

Cardiac Surgical Procedures*
Heart Valve Prosthesis Implantation*
Humans
Mitral Valve Insufficiency / surgery*
Treatment Outcome
Ventricular Remodeling